Meyer began playing the clarinet at an early age. Her first teacher was her father, also a clarinetist. She studied with Otto Hermann in Stuttgart and then with Hans Deinzer at the Hochschule für Musik und Theater, Hannover, along with her brother, clarinetist Wolfgang Meyer, and now-husband, clarinetist Reiner Wehle, who played later in the Munich Philharmonic. She began her career as a member of the Bayerische Rundfunk Symphony Orchestra and the Berlin Philharmonic, where her appointment as one of the orchestra's first female members caused controversy. Herbert von Karajan, the orchestra's music director, hired Meyer in September 1982, but the players voted against her at the conclusion of her probation period by a vote of 73 to 4. The orchestra insisted the reason was that her tone did not blend with the other members of the section, but other observers, including Karajan, believed that the true reason was her gender. In 1983, after nine months, Meyer left the orchestra to become a full-time solo clarinetist.

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